Designing disorder
نویسندگان
چکیده
منابع مشابه
Designing disorder
IDPs are abundant in all eukaryotic proteomes. Short ID regions mediate some 40% of all protein-protein interactions, for instance in regulatory tails of proteins. Large ID regions occur in essential scaffolds and molecular chaperones. What makes IDPs special? IDPs don’t form rigid hydrophobic cores due to lower fractions of hydrophobic and aromatic residues (W, I, Y, F, L, H, V). They are ofte...
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ژورنال
عنوان ژورنال: Intrinsically Disordered Proteins
سال: 2013
ISSN: 2169-0707
DOI: 10.4161/idp.26790